R49P (p.Arg49Pro) variant of IRF7 (Interferon regulatory factor 7)
R49P (p.Arg49Pro) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
R49P (p.Arg49Pro) variant details
- p.Arg49Pro
- ExAC rs749759655
- TOPMed rs749759655
- gnomAD rs749759655
- Missense
- Variant Prioritization Score for Impact Estimate 0.763
- AlphaMissense 0.97
- MetaLR 0.96
- MetaSVM 1.09
- CADD 24.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available