R41H (p.Arg41His) variant of IRF7 (Interferon regulatory factor 7)
R41H (p.Arg41His) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
R41H (p.Arg41His) variant details
- p.Arg41His
- ExAC rs747813321
- gnomAD rs747813321
- Missense
- Variant Prioritization Score for Impact Estimate 0.822
- AlphaMissense 0.71
- MetaLR 0.96
- MetaSVM 1.09
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.2e-05)
- Structural context available