R41C (p.Arg41Cys) variant of IRF7 (Interferon regulatory factor 7)
R41C (p.Arg41Cys) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
R41C (p.Arg41Cys) variant details
- p.Arg41Cys
- gnomAD rs1397863257
- Missense
- Variant Prioritization Score for Impact Estimate 0.809
- AlphaMissense 0.62
- MetaLR 0.95
- MetaSVM 1.06
- CADD 26.10
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available