R11P (p.Arg11Pro) variant of IRF7 (Interferon regulatory factor 7)
R11P (p.Arg11Pro) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
R11P (p.Arg11Pro) variant details
- p.Arg11Pro
- TOPMed rs1856773081
- gnomAD rs1856773081
- Missense
- Variant Prioritization Score for Impact Estimate 0.731
- AlphaMissense 0.47
- MetaLR 0.96
- MetaSVM 1.08
- CADD 24.80
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available