R104L (p.Arg104Leu) variant of IRF7 (Interferon regulatory factor 7)
R104L (p.Arg104Leu) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R104L (p.Arg104Leu) variant details
- p.Arg104Leu
- ExAC rs773728605
- gnomAD rs773728605
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- AlphaMissense 0.17
- MetaLR 0.85
- MetaSVM 0.38
- CADD 11.80
- PolyPhen-2 0.86
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.1e-05)
- Structural context available