R100G (p.Arg100Gly) variant of IRF7 (Interferon regulatory factor 7)
R100G (p.Arg100Gly) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
R100G (p.Arg100Gly) variant details
- p.Arg100Gly
- ExAC rs757871091
- TOPMed rs757871091
- gnomAD rs757871091
- Missense
- Variant Prioritization Score for Impact Estimate 0.461
- AlphaMissense 0.31
- MetaLR 0.89
- MetaSVM 0.46
- CADD 16.40
- PolyPhen-2 0.84
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available