P80T (p.Pro80Thr) variant of IRF7 (Interferon regulatory factor 7)
P80T (p.Pro80Thr) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
P80T (p.Pro80Thr) variant details
- p.Pro80Thr
- ExAC rs762601707
- gnomAD rs762601707
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- AlphaMissense 0.08
- MetaLR 0.85
- MetaSVM 0.10
- CADD 9.05
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available