P79L (p.Pro79Leu) variant of IRF7 (Interferon regulatory factor 7)
P79L (p.Pro79Leu) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P79L (p.Pro79Leu) variant details
- p.Pro79Leu
- gnomAD rs868179711
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- AlphaMissense 0.08
- MetaLR 0.77
- MetaSVM -0.35
- CADD 0.17
- PolyPhen-2 0.02
- SIFT 0.07
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available