P71T (p.Pro71Thr) variant of IRF7 (Interferon regulatory factor 7)
P71T (p.Pro71Thr) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
P71T (p.Pro71Thr) variant details
- p.Pro71Thr
- ExAC rs777886720
- TOPMed rs777886720
- gnomAD rs777886720
- Missense
- Variant Prioritization Score for Impact Estimate 0.689
- AlphaMissense 0.47
- MetaLR 0.86
- MetaSVM 0.55
- CADD 23.80
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available