P5S (p.Pro5Ser) variant of IRF7 (Interferon regulatory factor 7)
P5S (p.Pro5Ser) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
P5S (p.Pro5Ser) variant details
- p.Pro5Ser
- Ensembl rs1856783299
- Missense
- Variant Prioritization Score for Impact Estimate 0.266
- AlphaMissense 0.08
- MetaLR 0.61
- MetaSVM -0.42
- CADD 8.03
- PolyPhen-2 0.01
- SIFT 0.78
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available