P10R (p.Pro10Arg) variant of IRF7 (Interferon regulatory factor 7)
P10R (p.Pro10Arg) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
P10R (p.Pro10Arg) variant details
- p.Pro10Arg
- ESP rs375150065
- ExAC rs375150065
- TOPMed rs375150065
- gnomAD rs375150065
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- AlphaMissense 0.13
- MetaLR 0.75
- MetaSVM 0.25
- CADD 22.50
- PolyPhen-2 0.95
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 0.00039)
- Structural context available