L108M (p.Leu108Met) variant of IRF7 (Interferon regulatory factor 7)
L108M (p.Leu108Met) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
L108M (p.Leu108Met) variant details
- p.Leu108Met
- gnomAD rs1160725232
- Missense
- Variant Prioritization Score for Impact Estimate 0.511
- REVEL 0.38
- AlphaMissense 0.32
- MetaLR 0.91
- MetaSVM 0.79
- CADD 21.10
- PolyPhen-2 0.99
- Population evidence available
- Structural context available