K50R (p.Lys50Arg) variant of IRF7 (Interferon regulatory factor 7)
K50R (p.Lys50Arg) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
K50R (p.Lys50Arg) variant details
- p.Lys50Arg
- Ensembl rs1856762995
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- AlphaMissense 0.10
- MetaLR 0.74
- MetaSVM -0.15
- CADD 11.60
- PolyPhen-2 0.00
- SIFT 0.52
- Population evidence available
- Structural context available