G90V (p.Gly90Val) variant of IRF7 (Interferon regulatory factor 7)
G90V (p.Gly90Val) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
G90V (p.Gly90Val) variant details
- p.Gly90Val
- ExAC rs745658182
- TOPMed rs745658182
- gnomAD rs745658182
- Missense
- Variant Prioritization Score for Impact Estimate 0.514
- AlphaMissense 0.37
- MetaLR 0.79
- MetaSVM 0.33
- CADD 22.70
- PolyPhen-2 1.00
- SIFT 0.08
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available