G90D (p.Gly90Asp) variant of IRF7 (Interferon regulatory factor 7)
G90D (p.Gly90Asp) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
G90D (p.Gly90Asp) variant details
- p.Gly90Asp
- ExAC rs745658182
- TOPMed rs745658182
- gnomAD rs745658182
- Missense
- Variant Prioritization Score for Impact Estimate 0.544
- AlphaMissense 0.82
- MetaLR 0.86
- MetaSVM 0.54
- CADD 22.60
- PolyPhen-2 0.99
- SIFT 0.09
- Population evidence available
- Structural context available