G78S (p.Gly78Ser) variant of IRF7 (Interferon regulatory factor 7)
G78S (p.Gly78Ser) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
G78S (p.Gly78Ser) variant details
- p.Gly78Ser
- TOPMed rs1038112872
- gnomAD rs1038112872
- Missense
- Variant Prioritization Score for Impact Estimate 0.59
- AlphaMissense 0.09
- MetaLR 0.75
- MetaSVM 0.20
- CADD 7.04
- PolyPhen-2 0.01
- SIFT 0.71
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.4e-05)
- Structural context available