G78C (p.Gly78Cys) variant of IRF7 (Interferon regulatory factor 7)
G78C (p.Gly78Cys) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
G78C (p.Gly78Cys) variant details
- p.Gly78Cys
- TOPMed rs1038112872
- gnomAD rs1038112872
- Missense
- Variant Prioritization Score for Impact Estimate 0.678
- AlphaMissense 0.12
- MetaLR 0.87
- MetaSVM 0.38
- CADD 16.00
- PolyPhen-2 0.81
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available