G77D (p.Gly77Asp) variant of IRF7 (Interferon regulatory factor 7)
G77D (p.Gly77Asp) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
G77D (p.Gly77Asp) variant details
- p.Gly77Asp
- ExAC rs757334669
- TOPMed rs757334669
- gnomAD rs757334669
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- AlphaMissense 0.10
- MetaLR 0.93
- MetaSVM 0.26
- CADD 11.30
- PolyPhen-2 0.95
- SIFT 0.61
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available