G68D (p.Gly68Asp) variant of IRF7 (Interferon regulatory factor 7)
G68D (p.Gly68Asp) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
G68D (p.Gly68Asp) variant details
- p.Gly68Asp
- TOPMed rs1284583225
- gnomAD rs1284583225
- Missense
- Variant Prioritization Score for Impact Estimate 0.845
- AlphaMissense 0.84
- MetaLR 0.97
- MetaSVM 1.08
- CADD 26.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available