G25D (p.Gly25Asp) variant of IRF7 (Interferon regulatory factor 7)
G25D (p.Gly25Asp) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
G25D (p.Gly25Asp) variant details
- p.Gly25Asp
- ESP rs368359584
- ExAC rs368359584
- TOPMed rs368359584
- gnomAD rs368359584
- Missense
- Variant Prioritization Score for Impact Estimate 0.799
- AlphaMissense 0.59
- MetaLR 0.96
- MetaSVM 1.08
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available