G25A (p.Gly25Ala) variant of IRF7 (Interferon regulatory factor 7)
G25A (p.Gly25Ala) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
G25A (p.Gly25Ala) variant details
- p.Gly25Ala
- ESP rs368359584
- ExAC rs368359584
- TOPMed rs368359584
- gnomAD rs368359584
- Missense
- Variant Prioritization Score for Impact Estimate 0.781
- AlphaMissense 0.44
- MetaLR 0.95
- MetaSVM 1.06
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available