G20E (p.Gly20Glu) variant of IRF7 (Interferon regulatory factor 7)
G20E (p.Gly20Glu) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
G20E (p.Gly20Glu) variant details
- p.Gly20Glu
- TOPMed rs898220003
- gnomAD rs898220003
- Missense
- Variant Prioritization Score for Impact Estimate 0.637
- AlphaMissense 0.23
- MetaLR 0.80
- MetaSVM 0.11
- CADD 12.10
- PolyPhen-2 1.00
- SIFT 0.98
- Most common in the Finnish in Finland (FIN) population (allele frequency 4.5e-05)
- Structural context available