G15V (p.Gly15Val) variant of IRF7 (Interferon regulatory factor 7)
G15V (p.Gly15Val) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
G15V (p.Gly15Val) variant details
- p.Gly15Val
- TOPMed rs1244336930
- gnomAD rs1244336930
- Missense
- Variant Prioritization Score for Impact Estimate 0.568
- AlphaMissense 0.76
- MetaLR 0.91
- MetaSVM 0.83
- CADD 21.70
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available