G15E (p.Gly15Glu) variant of IRF7 (Interferon regulatory factor 7)
G15E (p.Gly15Glu) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
G15E (p.Gly15Glu) variant details
- p.Gly15Glu
- TOPMed rs1244336930
- gnomAD rs1244336930
- cosmic curated COSV52752
- Missense
- Variant Prioritization Score for Impact Estimate 0.582
- AlphaMissense 0.86
- MetaLR 0.93
- MetaSVM 0.88
- CADD 22.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available