G15A (p.Gly15Ala) variant of IRF7 (Interferon regulatory factor 7)
G15A (p.Gly15Ala) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
G15A (p.Gly15Ala) variant details
- p.Gly15Ala
- TOPMed rs1244336930
- gnomAD rs1244336930
- Missense
- Variant Prioritization Score for Impact Estimate 0.522
- AlphaMissense 0.23
- MetaLR 0.90
- MetaSVM 0.73
- CADD 20.30
- PolyPhen-2 1.00
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available