F60L (p.Phe60Leu) variant of IRF7 (Interferon regulatory factor 7)
F60L (p.Phe60Leu) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
F60L (p.Phe60Leu) variant details
- p.Phe60Leu
- gnomAD rs1446529694
- Missense
- Variant Prioritization Score for Impact Estimate 0.599
- AlphaMissense 1.00
- MetaLR 0.98
- MetaSVM 1.09
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available