E84D (p.Glu84Asp) variant of IRF7 (Interferon regulatory factor 7)
E84D (p.Glu84Asp) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
E84D (p.Glu84Asp) variant details
- p.Glu84Asp
- 1000Genomes rs545822500
- TOPMed rs545822500
- gnomAD rs545822500
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- AlphaMissense 0.56
- MetaLR 0.73
- MetaSVM 0.02
- CADD 14.70
- PolyPhen-2 0.97
- SIFT 0.53
- Population evidence available
- Structural context available