E16D (p.Glu16Asp) variant of IRF7 (Interferon regulatory factor 7)
E16D (p.Glu16Asp) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
E16D (p.Glu16Asp) variant details
- p.Glu16Asp
- TOPMed rs1487053331
- gnomAD rs1487053331
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- AlphaMissense 0.12
- MetaLR 0.65
- MetaSVM -0.19
- CADD 9.19
- PolyPhen-2 0.00
- SIFT 0.58
- Population evidence available
- Structural context available