D56N (p.Asp56Asn) variant of IRF7 (Interferon regulatory factor 7)
D56N (p.Asp56Asn) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data and structural context.
D56N (p.Asp56Asn) variant details
- p.Asp56Asn
- ExAC rs764976479
- TOPMed rs764976479
- gnomAD rs764976479
- Missense
- Variant Prioritization Score for Impact Estimate 0.84
- AlphaMissense 0.91
- MetaLR 0.97
- MetaSVM 1.09
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available