D51N (p.Asp51Asn) variant of IRF7 (Interferon regulatory factor 7)
D51N (p.Asp51Asn) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
D51N (p.Asp51Asn) variant details
- p.Asp51Asn
- TOPMed rs1856762706
- Missense
- Variant Prioritization Score for Impact Estimate 0.681
- AlphaMissense 0.56
- MetaLR 0.94
- MetaSVM 1.04
- CADD 22.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available