D34E (p.Asp34Glu) variant of IRF7 (Interferon regulatory factor 7)
D34E (p.Asp34Glu) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
D34E (p.Asp34Glu) variant details
- p.Asp34Glu
- TOPMed rs878869194
- gnomAD rs878869194
- Missense
- Variant Prioritization Score for Impact Estimate 0.422
- AlphaMissense 0.90
- MetaLR 0.92
- MetaSVM 0.84
- CADD 14.00
- PolyPhen-2 0.69
- SIFT 0.10
- Population evidence available
- Structural context available