C39R (p.Cys39Arg) variant of IRF7 (Interferon regulatory factor 7)
C39R (p.Cys39Arg) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
C39R (p.Cys39Arg) variant details
- p.Cys39Arg
- ExAC rs772662853
- TOPMed rs772662853
- gnomAD rs772662853
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- AlphaMissense 0.10
- MetaLR 0.55
- MetaSVM -0.06
- CADD 13.70
- PolyPhen-2 0.00
- SIFT 0.78
- Most common in the Non-Finnish European population (allele frequency 8.1e-06)
- Structural context available