A89T (p.Ala89Thr) variant of IRF7 (Interferon regulatory factor 7)
A89T (p.Ala89Thr) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
A89T (p.Ala89Thr) variant details
- p.Ala89Thr
- TOPMed rs1327288971
- gnomAD rs1327288971
- Missense
- Variant Prioritization Score for Impact Estimate 0.585
- AlphaMissense 0.48
- MetaLR 0.91
- MetaSVM 0.98
- CADD 23.30
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available