A89P (p.Ala89Pro) variant of IRF7 (Interferon regulatory factor 7)
A89P (p.Ala89Pro) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
A89P (p.Ala89Pro) variant details
- p.Ala89Pro
- TOPMed rs1327288971
- gnomAD rs1327288971
- Missense
- Variant Prioritization Score for Impact Estimate 0.592
- AlphaMissense 0.50
- MetaLR 0.92
- MetaSVM 1.02
- CADD 23.60
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available