A66V (p.Ala66Val) variant of IRF7 (Interferon regulatory factor 7)
A66V (p.Ala66Val) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
A66V (p.Ala66Val) variant details
- p.Ala66Val
- gnomAD rs1194352093
- Missense
- Variant Prioritization Score for Impact Estimate 0.686
- AlphaMissense 0.38
- MetaLR 0.88
- MetaSVM 0.68
- CADD 22.30
- PolyPhen-2 1.00
- SIFT 0.13
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available