A4V (p.Ala4Val) variant of IRF7 (Interferon regulatory factor 7)
A4V (p.Ala4Val) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
A4V (p.Ala4Val) variant details
- p.Ala4Val
- ExAC rs776893144
- gnomAD rs776893144
- Missense
- Variant Prioritization Score for Impact Estimate 0.544
- AlphaMissense 0.23
- MetaLR 0.79
- MetaSVM 0.16
- CADD 6.30
- PolyPhen-2 0.00
- SIFT 0.22
- Most common in the Latino/Admixed American population (allele frequency 3e-05)
- Structural context available