A36T (p.Ala36Thr) variant of IRF7 (Interferon regulatory factor 7)
A36T (p.Ala36Thr) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
A36T (p.Ala36Thr) variant details
- p.Ala36Thr
- TOPMed rs1856766807
- Missense
- Variant Prioritization Score for Impact Estimate 0.553
- AlphaMissense 0.10
- MetaLR 0.93
- MetaSVM 0.95
- CADD 24.20
- PolyPhen-2 1.00
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available