A36D (p.Ala36Asp) variant of IRF7 (Interferon regulatory factor 7)
A36D (p.Ala36Asp) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
A36D (p.Ala36Asp) variant details
- p.Ala36Asp
- gnomAD rs1253897149
- Missense
- Variant Prioritization Score for Impact Estimate 0.5
- AlphaMissense 0.12
- MetaLR 0.85
- MetaSVM 0.35
- CADD 22.60
- PolyPhen-2 1.00
- SIFT 0.78
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available