W17C (p.Trp17Cys) variant of IL33 (Interleukin-33)
W17C (p.Trp17Cys) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
W17C (p.Trp17Cys) variant details
- p.Trp17Cys
- ExAC rs763483741
- TOPMed rs763483741
- gnomAD rs763483741
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- AlphaMissense 0.17
- MetaLR 0.05
- MetaSVM -1.05
- CADD 10.80
- PolyPhen-2 0.00
- SIFT 0.02
- Most common in the East Asian population (allele frequency 5.1e-05)
- Structural context available