W17* (p.Trp17Ter) variant of IL33 (Interleukin-33)
W17* (p.Trp17Ter) in IL33 (Interleukin-33) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
W17* (p.Trp17Ter) variant details
- p.Trp17Ter
- ExAC rs776153612
- gnomAD rs776153612
- NCI-TCGA TCGA novel
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.0818
- CADD 0.16
- UniProt: Variant assessed as somatic; high impact.
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available