T65I (p.Thr65Ile) variant of IL33 (Interleukin-33)
T65I (p.Thr65Ile) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
T65I (p.Thr65Ile) variant details
- p.Thr65Ile
- ExAC rs778113447
- gnomAD rs778113447
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- AlphaMissense 0.19
- MetaLR 0.17
- MetaSVM -0.92
- CADD 15.60
- PolyPhen-2 0.94
- SIFT 0.01
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available