S49T (p.Ser49Thr) variant of IL33 (Interleukin-33)
S49T (p.Ser49Thr) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
S49T (p.Ser49Thr) variant details
- p.Ser49Thr
- ExAC rs759104347
- gnomAD rs759104347
- Missense
- Variant Prioritization Score for Impact Estimate 0.536
- AlphaMissense 0.25
- MetaLR 0.28
- MetaSVM -0.68
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available