S32C (p.Ser32Cys) variant of IL33 (Interleukin-33)
S32C (p.Ser32Cys) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
S32C (p.Ser32Cys) variant details
- p.Ser32Cys
- ExAC rs750639062
- TOPMed rs750639062
- gnomAD rs750639062
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- AlphaMissense 0.11
- MetaLR 0.15
- MetaSVM -0.94
- CADD 14.10
- PolyPhen-2 0.45
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 5.6e-05)
- Structural context available