S22R (p.Ser22Arg) variant of IL33 (Interleukin-33)
S22R (p.Ser22Arg) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
S22R (p.Ser22Arg) variant details
- p.Ser22Arg
- TOPMed rs1219952994
- gnomAD rs1219952994
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- AlphaMissense 0.25
- MetaLR 0.07
- MetaSVM -1.01
- CADD 13.20
- PolyPhen-2 0.36
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available