R62S (p.Arg62Ser) variant of IL33 (Interleukin-33)
R62S (p.Arg62Ser) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
R62S (p.Arg62Ser) variant details
- p.Arg62Ser
- gnomAD 9-6250568-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- AlphaMissense 0.27
- MetaLR 0.07
- MetaSVM -1.03
- CADD 15.60
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available