R61T (p.Arg61Thr) variant of IL33 (Interleukin-33)
R61T (p.Arg61Thr) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
R61T (p.Arg61Thr) variant details
- p.Arg61Thr
- gnomAD 9-6250564-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- AlphaMissense 0.19
- MetaLR 0.20
- MetaSVM -0.91
- CADD 18.30
- PolyPhen-2 0.96
- SIFT 0.02
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available