R61K (p.Arg61Lys) variant of IL33 (Interleukin-33)
R61K (p.Arg61Lys) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R61K (p.Arg61Lys) variant details
- p.Arg61Lys
- gnomAD rs1329680063
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- AlphaMissense 0.11
- MetaLR 0.10
- MetaSVM -1.06
- CADD 7.81
- PolyPhen-2 0.09
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available