M5V (p.Met5Val) variant of IL33 (Interleukin-33)
M5V (p.Met5Val) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
M5V (p.Met5Val) variant details
- p.Met5Val
- ExAC rs747277388
- TOPMed rs747277388
- gnomAD rs747277388
- Missense
- Variant Prioritization Score for Impact Estimate 0.492
- AlphaMissense 0.12
- MetaLR 0.09
- MetaSVM -1.04
- CADD 17.40
- PolyPhen-2 0.55
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00018)
- Structural context available