M5R (p.Met5Arg) variant of IL33 (Interleukin-33)
M5R (p.Met5Arg) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
M5R (p.Met5Arg) variant details
- p.Met5Arg
- ExAC rs771108276
- gnomAD rs771108276
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- AlphaMissense 0.19
- MetaLR 0.12
- MetaSVM -0.93
- CADD 19.20
- PolyPhen-2 0.18
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available