M52L (p.Met52Leu) variant of IL33 (Interleukin-33)
M52L (p.Met52Leu) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
M52L (p.Met52Leu) variant details
- p.Met52Leu
- ExAC rs762904713
- TOPMed rs762904713
- gnomAD rs762904713
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- AlphaMissense 0.12
- MetaLR 0.04
- MetaSVM -1.02
- CADD 7.12
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available